Healthcare AI Guy Weekly | 7/1

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Our Picks ✨

Highlights if you’ve only got 2 minutes…

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Medical superintelligence

Microsoft’s new health AI system, MAI-DxO, just took on one of the hardest challenges in medicine: 304 real diagnostic cases from the New England Journal of Medicine. These aren’t simple multiple-choice questions, they require step-by-step reasoning, asking the right follow-up questions, and choosing tests wisely. When paired with OpenAI’s o3, the AI solved 85.5% of cases, compared to just 20% by experienced doctors. Essentially, AI had 4x higher accuracy with 20% lower cost. MAI-DxO works like a virtual panel of physicians with different thinking styles, collaborating to reach a diagnosis. The research is early, but it’s a big step toward faster, smarter, and more affordable care. As these tools improve, they could expand access to high-quality care around the world and become the new gold standard in diagnosis. (link)(linkedin)

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DeepMind unveils AlphaGenome

Google DeepMind just released AlphaGenome, a powerful new AI model that reads up to 1 million base-pairs of DNA and predicts how mutations affect thousands of molecular processes. Unlike older tools, it does not just analyze single genes. It captures how changes ripple across the entire regulatory genome. In testing, it helped explain how specific mutations activate cancer-linked genes and outperformed nearly every specialized model across benchmarks, using only half the compute of its predecessor. By unifying multiple prediction tasks into one tool, AlphaGenome speeds up research into rare diseases, gene regulation, and potential therapies. While not built for clinical use, it gives scientists a fast and scalable way to explore the molecular impact of genetic variation. DNA is code, and AlphaGenome brings us one step closer to programmable biology. (link)

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Labcorp enters the chat

Labcorp just entered the longevity testing space in a big way with Whole Health Solutions, a direct-to-consumer offering that includes over 1,000 biomarkers. It covers much of what startups like Function Health, Superpower, and others provide but straight from the source. While the big labs have been slow to modernize on things like APIs, they’ve steadily expanded into consumer-friendly services. Many longevity startups built strong experiences on top of Labcorp and Quest infrastructure, adding value through design, education, and engagement. But with an $8 billion market on the table, the labs may start leaning in more. The companies that thrive will be the ones that go beyond ordering tests, offering real insights, clinical guidance, and longitudinal care. As labs go direct, the real value will shift to interpretation, guidance, and long-term health outcomes. We still think the startups are well-positioned to win here, but it’s a shift worth watching closely as the space continues to evolve. (link)(tweet)

Tools & Partnerships 🔧

Latest on business, consumer, and clinical healthcare AI tools and partnerships…

TOOLS

• Optum launches AI marketplace: Optum unveiled a marketplace for vetted AI tools from partners like Microsoft and Google, covering claims, analytics, and care management, with sandbox testing and secure APIs. (link)

• Dartmouth Health debuts LLM for patient messages: Dartmouth built an LLM-based triage tool to assess patient portal messages, determine urgency, and craft follow-up questions—improving speed and access to care. (link)

• Insight Health launches AI agents for intake: Insight released AI tools to automate patient intake, surveys, and follow-ups. The goal: reduce admin load, cut wait times, and enhance patient engagement across visits. (link)

• Commure rolls out AI agents after $200M raise: Commure launched AI agents for physician workflows like referrals and documentation to reduce EHR time, improve productivity, and combat clinician burnout. (link)

• Sentara uses AI for discharge summaries and EHRs: Sentara’s pilot surfaced key clinical insights and drafted discharge notes using AI—seeing 75%+ adoption. It's now scaling the tech across more workflows. (link)

• Collectly launches Billie, AI billing voice agent: Collectly introduced Billie, an AI voice agent that handles billing questions and payment calls—expanding automation tools for revenue cycle ops. (link)

• City of Hope launches HopeLLM for research and trials: HopeLLM powers patient-trial matching, medical record summarization, and data structuring—now live across City of Hope’s nationwide research sites. (link)

• Reid Hoffman backs AI brain-stim helmet startup: Sanmai raised $12M from Reid Hoffman to develop an AI-powered ultrasound helmet that offers noninvasive brain stimulation for anxiety and depression. (link)

• St. Luke’s boosts revenue with ambient AI notes: St. Luke’s generated $13K per clinician using Ambience’s AI notes, cutting charting time 41%, reducing burnout, and increasing time for patient care. (link)

• Northwestern builds low-cost AI for radiology: Northwestern’s in-house AI drafts 95% of imaging reports using Meta’s open-source model—raising radiologist output by 40% at 100x lower cost. (link)

• Ambience debuts “Patient Recap” AI at St. Luke’s: Ambience launched the first ambient AI tool to generate pre-visit chart summaries, aiming to extend clinical efficiency beyond documentation. (link)

• Cairns Health releases Luna, AI for elder care: Luna is a digital companion for seniors and caregivers, offering AI-guided support for daily tasks, health monitoring, and in-home care navigation. (link)

• Anthropic finds AI support chats improve mood: Claude chats tagged as emotional support made up just 2.9% of use but saw increasing positivity over time—suggesting potential in low-risk AI care support. (link)

• DeepSeek R1, o3-mini top Stanford MedHELM test: In a benchmark of 9 models on 121 tasks, DeepSeek R1 had the highest win rate; o3-mini led in average accuracy. Reasoning-focused LLMs outperformed in clinical use. (link)

PARTNERSHIPS

• Cleveland Clinic + Ambience Healthcare: Cleveland Clinic has onboarded over 4,000 physicians (with 2K trained already) to Ambience’s AI scribe platform after a rigorous evaluation across 80+ specialties—streamlining documentation, reducing clinician burden, and improving patient interactions. (link)

• Arkansas Children’s + Caregility: Arkansas Children’s is deploying Caregility’s ambient AI-enabled virtual care platform in its NICU to support teleresuscitation, specialist consults, and telesimulation for critically ill infants. (link)

• Aidoc + NVIDIA: Aidoc launched BRIDGE, a new framework co-developed with NVIDIA to support safe, scalable AI deployment in clinical workflows across health systems. (link)

• Hellocare + Mayo Clinic: Mayo Clinic is partnering with Hellocare to advance ambient clinical intelligence for early detection and clinician support, while also joining the company’s recent $47M growth round. (link)

• Erlanger Health + Qventus: Erlanger Health is expanding its use of Qventus’ AI platform to optimize OR scheduling, boost robotic surgery access, and increase surgical throughput. (link)

• Sutter Health + Aidoc: Sutter Health is partnering with Aidoc to deploy its AI operating system across the enterprise, accelerating triage for critical conditions. (link)

Deal Desk 💸 

Spotlight on latest capital raises, M&A, and investments…

FUNDING

• Abridge, a Pittsburgh-based AI-powered healthcare technology company, raised $300M in Series E funding. a16z led the round and was joined by Khosla Ventures. (link)

• Decagon, a San Francisco-based customer experience conversational AI platform, raised $131M in Series C funding at a $1.5B valuation. Accel and Andreessen Horowitz led the round and were joined by others. (link)

• ForSight Robotics, an Israel-based AI-powered robotic eye surgery tech provider, raised $125M in Series B funding. Eclipse led the round and was joined by others. (link)

• Mandolin, an AI automation platform for specialty drug access, raised $40M from Greylock, SignalFire, SV Angel, and Maverick. (link)

• Arine, a San Francisco-based AI-powered medication intelligence platform, raised $30M in Series C funding. Town Hall Ventures led the round and was joined by Kaiser Permanente Ventures and other existing investors. (link)

• Synthflow AI, a Berlin-based agentic AI platform for phone call automation, raised $20M in Series A funding. Accel led the round and was joined by existing investors Atlantic Labs and Singular. (link)

• SuperDial, a San Francisco-based voice AI platform for healthcare administration, raised $12M in Series A funding. SignalFire led the round and was joined by Slow Ventures, Box Group, and Scrub Capital. (link)

• Insight Health, an Austin-based AI agents developer for clinics, raised $4.6M in funding. Kindred Ventures led the round and was joined by others. (link)

• Voicecare AI, an SF-based agentic AI startup for health care admins, raised $4.5M in seed funding. Caduceus Capital Partners led, joined by Mayo Clinic and others. (link)

• NexusMD, a Melbourne-based agentic AI health care solutions provider, raised $4.1M in seed funding from Square Peg. (link)

• RevelAi Health, a conversational AI platform built for musculoskeletal care, raised a $3.1M seed round led by Ulu Ventures and Symphonic Capital. (link)

MERGERS & ACQUISITIONS

• General Catalyst + Summa Health: General Catalyst has officially secured approval to acquire Summa Health, giving it a real-world sandbox to build the tech-enabled hospital of the future across acute, critical, outpatient, ED, and home care. (link)

Other Relevant News 🔍

News, podcasts, blogs, tweets, resources, etc…

• AMA adopted a new policy for “explainable AI” in clinical care (link)

• AI and mobile tech take center stage at spring health conferences (link)

• Health systems turn to AI to improve safety and outcomes (link)

• AI in health is under-hyped, tech and hospital execs say at Aspen (link)

• AI won’t transform healthcare overnight, says Wellmark CIO (link)

• AI agents can help automate healthcare claims work (link)

AI Job Opportunities 💼 

Contact us to feature roles in our newsletter…

• Director of AI Engineering at Talkiatry, a digital health psychiatry company

  $230 - $270K | Remote (link)

• Founding Engineer at Autoblocks AI, an LLM proactive testing startup

  $NA | NYC (link)

• Product Manager (AI) at Atropos Health, a real-world evidence platform

  $100 - $125K | Remote (link)

• Growth & Partnerships at Decagon, a customer conversational AI platform

  $200 - $280K | San Francisco (link)

• Product Manager at Pearl AI, an AI-powered dental platform

  $NA | Remote (link)

Visuals of the Week 📸

Funny memes, cool pics, and interesting data from around the web…