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Welcome back, friends —

Hope everyone had a nice Memorial Day weekend! Here’s what we’ve been tracking:

IPO frenzy
OpenEvidence continues to expand
CNBC’s top healthcare AI disruptors
23 new tools/partnerships, 12 funding updates, new AI jobs & link-worthy content

Read time: 6 minutes

Our Picks ✨

Highlights if you’ve only got 2 minutes…

IPO frenzy

The AI IPO pipeline is starting to look historic. OpenAI is reportedly preparing to go public, Anthropic soon too and is currently fundraising at $900B, SpaceX has officially filed its S-1 targeting a $1.75-2T open, and wearable company Oura has confidentially filed after explosive growth. What stands out is how healthcare is embedded across all of these stories. They are becoming either directly or adjacent healthcare infrastructure, research, and consumer health platforms all at once.

OpenAI: The company is expanding across healthcare with ChatGPT for Healthcare, ChatGPT Health, and ChatGPT for Clinicians. It is already partnered with major systems like Cedars-Sinai, HCA, UCSF, and Memorial Sloan Kettering, while clinician usage of ChatGPT has more than doubled over the last year. (link)
Anthropic: Claude for Healthcare is already being used at Banner Health, Stanford Health Care, CommonSpirit, and others for workflows like oncology summaries, call center support, and revenue cycle operations. Anthropic is also becoming a major infrastructure customer, reportedly spending around $1.5B annually on compute tied to SpaceX’s Colossus data center. (link)
SpaceX: Its S-1 explicitly highlighted healthcare AI as a major future use case, from medical analysis to scientific discovery. Beyond rockets, the company is quietly becoming a compute giant through Starlink, xAI, and Grok, giving it a powerful position in the long term AI infrastructure race. (link)(tweet)
Oura: Oura is nearing 5M paid members after growing revenue more than 4x in two years. It has expanded beyond just sleep tracking into metabolic health, fertility, stress, and cardiovascular monitoring, with partnerships across Dexcom, Maven Clinic, and the Department of Defense. (link)

The theme is that healthcare is now woven in deeply into the AI story and will be one of the most important battlegrounds in the race to build the next trillion dollar AI companies.

OpenEvidence continues to expand

OpenEvidence is shifting from being a popular physician search tool to becoming a much deeper part of clinical workflows. This past week, the company announced a new voice AI feature alongside a major Epic integration with Cedars-Sinai that brings patient-aware clinical reasoning directly into the chart.

The new Voice Mode lets clinicians ask questions hands-free while rounding or moving between patient visits. At Cedars-Sinai, OpenEvidence is now embedded directly into Epic, combining peer-reviewed medical literature with patient context including medications, allergies, prior procedures, comorbidities, and longitudinal chart data.

What’s notable is that most clinical AI tools still sit outside the EHR, meaning they can answer general questions but lack awareness of what is actually happening with a patient. OpenEvidence can now retrieve patient-specific data, interpret it against current evidence, and return more tailored clinical guidance.

The company says roughly 65% of U.S. physicians used the platform across 27M clinical encounters in April alone. Let’s see where they go from here. (link)(linkedin)

CNBC’s top healthcare AI disruptors

Several startups with ties to healthcare made CNBC’s recent annual Disruptor 50 rankings, highlighting the continued importance behind AI-powered care delivery, research, diagnostics, and consumer health. Anthropic overtook OpenAI for the No. 1 spot in 2026, with both companies recently expanding into healthcare. Below are the 12 AI in healthcare-related winners. (link)(linkedin)

Anthropic — frontier AI lab
OpenAI — frontier AI lab
Sierra — conversational AI agents for customer experience and support
Transcarent — digital healthcare and benefits navigation platform
ŌURA — smart wearable platform for sleep, recovery, and health tracking
Lila Sciences — autonomous AI-powered scientific research & discovery platform
Abridge — ambient AI for clinical documentation and medical conversations
Perplexity — AI-native search and answer engine
OpenEvidence — AI-powered clinical search engine for clinicians
Iambic — AI-driven platform for drug discovery and therapeutics design
Decagon — AI customer support agents for enterprise operations
WHOOP — connected fitness and biometric performance platform

Tools & Partnerships 🔧

Latest on business, consumer, and clinical healthcare AI tools and partnerships…

TOOLS

NVIDIA open-sources synthetic medical imaging tools: New models generate realistic 3D CT and MRI scans with segmentation masks to help train medical AI systems without relying on patient data. (link)
Doctors frame autonomous vehicles as a public health issue: Clinicians including Eric Topol and Jonathan Slotkin are urging regulators to support AV deployment, citing evidence that driverless vehicles reduce serious crashes and pedestrian injuries. (link)
Fake AI-generated citations are spreading in medical research: A Lancet audit identified more than 4,000 fabricated citations across peer-reviewed papers, raising concerns about LLM-written content influencing clinical guidelines. (link)
Mayo Clinic uses AI to expand palliative care: An AI “heat map” tool increased timely referrals by 44% and reduced readmissions by helping clinicians identify patients with unmet supportive care needs earlier. (link)
Google unveils major Gemini AI upgrades: New releases include Gemini Omni for multimodal video generation, Spark personal agents, and expanded agentic Search features. (link)
UnitedHealth tracks employee AI adoption: Reports say Optum is monitoring how often some staff use tools like ChatGPT and Copilot as AI becomes more embedded in workflows. (link)
Canvas Medical launches no-code AI workflow builder: Canvas Studio lets clinicians create custom EMR workflows and agentic automations using natural language instead of developers. (link)
Neuralink unveils next-gen brain implant robot: The updated surgical robot can access nearly any brain region and automate key parts of Neuralink’s implant procedure. (link)
Cleveland Clinic co-develops cardiac MRI AI model: Researchers trained an AI system on MRI images and radiology reports, achieving 99% accuracy without manual labeling. (link)
Labcorp launches AI-powered health app: MyLabcorp uses OpenAI models to help consumers interpret lab results and track health trends over time. (link)
Employers ramp up AI use in benefits: A WTW survey found 72% of employers plan to embed AI into health and benefits programs within two years. (link)
AI detector spots deepfake medical images: AI or Not reportedly achieved perfect accuracy detecting synthetic radiology images from a recent deepfake study. (link)
AI avatars may improve cancer consult prep: An ESTRO study found patients receiving radiation oncology education from AI doctor avatars had better understanding and lower stress. (link)
OpenAI sued over alleged harmful drug advice: Parents filed suit claiming ChatGPT provided dangerous recommendations that contributed to their son’s fatal overdose. (link)
Google publishes AI Co-Scientist research: Gemini-powered system uses “idea tournaments” between agents to generate and refine scientific hypotheses for biology research. (link)

PARTNERSHIPS

Providence + Ksana Health: Providence partnered with Ksana Health on a federally funded AI initiative to predict and manage mental health and substance use crises using behavioral and EHR data. (link)
Ksana Health + Providence + MedStar + UW: Ksana Health received $17.9M to partner with Providence, MedStar, and UW on AI foundation models for mental health and substance use care using smartphone, wearable, and EHR data. (link)
UnityAI + Spero Health: Spero Health deployed UnityAI’s PatientOps platform across 60+ locations to automate patient call handling and improve access to addiction treatment services. (link)
23andMe + HealthEx: 23andMe partnered with HealthEx to let users connect medical records with genetic profiles inside its AI Health Summary platform. (link)
Anthropic + Bristol Myers Squibb: Bristol Myers Squibb signed an enterprise AI deal with Anthropic to deploy Claude across drug discovery, clinical development, manufacturing, and commercial workflows. (link)
University of Michigan Health + Avenda Health: University of Michigan Health deployed Avenda Health’s Unfold AI platform to map prostate cancer in 3D for treatment planning. (link)
AdventHealth + OpenAI: AdventHealth deployed ChatGPT for Healthcare across its system to reduce administrative burden and streamline clinical workflows. (link)
MetroHealth + Artisight: MetroHealth partnered with Artisight to deploy smart hospital technology, including virtual nursing and AI-enabled patient monitoring, across five hospitals. (link)

Deal Desk 💰

Spotlight on latest capital raises, M&A, and investments…

FUNDING

Vi, an NYC-based maker of healthcare AI agents raised $145M at a $1.65B valuation from General Atlantic, Revelstoke, 1902 Capital, Square Peg, Savano Capital, and Island Green. (link)
Nourish, a NYC-based metabolic health clinic, raised $100M in Series C funding. Menlo Ventures led the round and was joined by Thrive Capital, Index Ventures, J.P. Morgan Growth Equity Partners, Maverick Ventures, Y Combinator, BoxGroup, Atomico, Daybreak, and Operator Partners. (link)
Commure, a Mountain View, Calif.-based health-care workflow platform, raised $70M at a $7B post-money valuation. General Catalyst led, joined by Sequoia Capital, Morgan Stanley ⁠and Kirkland & Ellis. (link)
The Path, an AI therapy platform co-founded by Tony Robbins, raised $14.3M in seed funding led by Prime Movers Labs. (link)
Vortex Imaging, a Sunnyvale, Calif.-based medical imaging startup, raised $12M from 10D Ventures, Entrée Capital, Harel T.E.C Partnership, Connecticut Innovations, and PhiFund Ventures. (link)
Neurosoft Bioelectronics, a Swiss brain-computer interface startup, raised a $7.5M in seed funding. Skybound Venture Capital led, joined by PL Capital, IAG Capital Partners, and Connecticut Innovations. (link)
Century Health, a NYC-based company applying AI to clinical data to accelerate research, raised $5M in seed funding. Origin Ventures led. (link)

MERGERS & ACQUISITIONS

Cohere + Reliant AI: Cohere acquired Reliant AI to expand its secure, domain-specific AI platform for biopharma R&D, clinical development, and scientific analytics. (link)
Gyde + We Know Medicare: Gyde acquired We Know Medicare to expand its AI-enabled Medicare brokerage platform and strengthen its national distribution network. (link)
Innovaccer + CaduceusHealth: Innovaccer acquired CaduceusHealth to combine AI-powered revenue cycle tools with ambulatory RCM services and human oversight. (link)
Qualtrics + Press Ganey Forsta: Qualtrics acquired Press Ganey Forsta for $6.75B to expand its AI-driven experience management platform with healthcare experience and patient feedback data. (link)
GHO Capital + CBC Group: GHO Capital and CBC Group plan to merge to create a $21B healthcare-focused investment firm spanning healthcare IT, life sciences, diagnostics, and medical devices. (link)